NMN Supplement Reviews (2024 Update) Best Brands on the Market to Use

No one can remain untouched with progressing age. The stress your physical and mental being goes through with age does irreparable damage to your cellular health. However, with the right NMN supplements, it is possible to support healthy aging.

Are you wondering what NMN supplements are? Nicotinamide Mononucleotide (NMN) is a precursor to NAD+. This naturally occurring molecule helps in the synthesis of Nicotinamide Adenine Dinucleotide when two NMN molecules are combined. Taking NMN supplements helps reverse the aging effects by promoting healthy aging, boosting cognitive health, increasing vitality, promoting insulin sensitivity, supporting energy metabolism, helping DNA repair, and more. You finally have the magical pill to regain your youth!

However, finding pure NMN products that contain pure NMN powder is not easy. You may find it difficult to compare NMN brands by yourself. Are NMN supplements safe? Are NMN supplements dangerous? How do NMN supplements work? Questions like this will plague your mind if you can’t find the right answers.

Hence, our team has compared the best NMN supplements against some ranking factors and created a list of the winners. Take a look at the best NMN supplements of 2023!

Best NMN Supplements That Are A Popular Choice In 2023

Some of the best NMN supplements of this year that are a popular choice among consumers are:

GenF20 Liposomal NMN+


Servings Per Container:


Money-Back Guarantee:



$69.95 (Official Website)

Liposomal NMN+ supplement is one of the best NMN supplements that you can find. This high-quality NMN supplement is named the new science to reverse your age and make you feel younger. GenF20 Liposomal NMN contains 98% pure NMN and is non-GMO.

The unique feature of this NMN supplement is that it contains liposomal which helps in increasing the bioavailability of NMN.

GenF20 Liposomal NMN supplements benefit your health in multiple ways. It powers up your mitochondria to produce cellular energy, promotes DNA repair, prevents aging at the cellular level, energizes your body, relieves joint pain, and promotes brain health.

The recommended NMN dose is one vegetarian capsule daily.

About The Brand

Liposomal NMN is manufactured by GenF20, a leading brand in the natural anti-aging industry that makes supplements to support your longevity genes. For over 20 years, GenF20 has been a trusted figure and one of the best NMN brands in the NMN supplements industry.

They are a pioneer in creating innovative and groundbreaking formulas to help people live their best lives. Their team includes researchers and scientists who are an expert in creating anti-aging dietary supplements.

The NMN supplement is manufactured in an FDA-approved facility in the USA and follows the Good Manufacturing Guidelines.

How It Works

The GenF20 Liposomal NMN supplement formula is backed by research and works to boost the level of NAD+ in your body. The added benefit of liposomal helps this supplement in better absorption of the nicotinamide mononucleotide as it increases the bioavailability of the compound.

The better absorption of NMN helps in increasing the NAD+ levels which rejuvenates your cells and supports energy production. Liposomal NMN helps your cells to regenerate to help you regain your youth and vitality.

Pros And Cons

Pros of GenF20 Liposomal NMN supplement are:

  • Multiple health benefits
  • Liposomal NMN supplement has no side effects
  • A 67-day money-back guarantee.

Cons of GenF20 Liposomal NMN supplement are:

  • The Liposomal NMN supplement may not work for all.

Tru Niagen


Servings Per Container:


Money-Back Guarantee:



$40 (Official Website)

Tru Niagen NMN supplement is another best NMN supplement that is our favorite. It is considered one of a one-of-a-kind NMN supplement. The special formula of Tru Niagen is carefully designed to tackle the aging problem at its root.

Available in capsule form, the supplement contains 300mg of Niagen and is clinically tested to be a safe option to give you the best aging experience.

The health benefits of Tru Niagen NMN usage include healthy aging, improved brain health, better cardiovascular health, improved immune system, and healthy mitochondria. The NMN dietary supplement can also help you counterbalance the stressors that you encounter every day.

As for the Tru Niagen NMN dosage, take 2-3 capsules daily.

About The Brand

ChromDex manufactures the Tru Niagen supplement. ChromaDex is a pioneer in the health supplement industry and for the past 25 years, they have been working relentlessly to discover effective and advanced health supplements. ChromaDex launched Tru Niagen in 2017 after they patented Niagen.

Tru Niagen has a team of brilliant scientists with Charles Brenner as their chief scientific advisor. Charles Brenner is the person who discovered the NAD-boosting potential of nicotinamide ribosome (NR), a variant of vitamin B3. Their research team is always striving to bring something new and better to consumers.

The supplement is manufactured in approved facilities and strictly follows the GMP guidelines.

How It Works

With age a decline in NAD+ levels can be observed. This can cause your cells to degenerate under metabolic and oxidative stress. Tru Niagen NMN supplement works to increase the NAD+ levels in your body so your cells can function smoothly.

By counterbalancing the stressors your body encounters, the supplement reduces the oxidative and metabolic stress on your cells and the abundant supply of NAD+ helps your cells regenerate and become healthy again to function properly to combat aging. Thus, Tru Niagen helps your 37.2 trillion cells combat the effects of aging.

Pros And Cons

Pros of Tru Niagen are:

  • The supplement is reasonably priced.
  • Clinically tested to be effective.

Cons of Tru Niagen are:

  • The statements made by the Tru Niagen NMN brand are not approved by the FDA.

Cymbiotika NMN + Trans Resveratrol


Amount Per Container:

60 Capsules

Money-Back Guarantee:



$77 (Official Website)

Our other favorite choice is the Cymbiotika NMN supplement. Unlike other supplements, this NMN supplement combines NMN with Trans-resveratrol to give you the best anti-aging care. Cymbiotika NMN Resveratrol is keto, vegan, and free of gluten or soy.

Regular NMN supplementation of Cymbiotika helps in energy production, maintaining healthy DNA, supporting cellular metabolism, and reducing oxidative stress. Trans-resveratrol may also help in promoting heart health, reducing weight, and expanding blood vessels. The combination of these benefits of NMN supplements by Cymbiotika helps you age beautifully.

The recommended NMN dose of Cymbiotika NMN supplement is two capsules daily.

About The Brand

Cymbiotika LLC manufactures this NMN supplement. The philosophy of this NMN brand is to live with intention and in harmony with nature. Cymbiotika believes in the power of a healthy diet packed with vital nutrients. As our modern diet lacks these nutrients, Cymbiotika strives to fill the nutrition gap with its supplements.

The NMN brand values transparency and trust above all. Their research team has combined traditional Chinese medicine with modern medicine to create the best NMN supplements with plant-based ingredients.

The supplement is manufactured in the USA in an FDA-approved facility and has been clinically tested to ensure the highest quality NMN supplements have to offer.

How It Works

NMN is one of the essential nutrients that your body needs. Cymbiotika NMN Resveratrol supplement supplies your body with ample NMN. With added polyphenols and antioxidants, Cymbiotika NMN Resveratrol boosts NAD levels easily.

This leads to healthy gene expression, energy production, and improved metabolism. By continuously supplying nicotinamide mononucleotide and biosynthesis of NAD+ to increase the NAD levels, Cymbiotika NMN Resveratrol helps repair your cells. Healthy cells can energize you and reverse the aging effects.

Pros and Cons:

Pros of Cymbiotika NMN are:

  • This best NMN supplement offers the added benefit of resveratrol.
  • Combined with a healthy and balanced diet, the supplement helps combat the aging effects efficiently.

Cons of Cymbiotika NMN are:

  • It contains caffeine so, people who are sensitive to caffeine may suffer.
  • The NMN Resveratrol supplement is not the right choice for pregnant or nursing mothers and people with medical conditions like diabetes, heart problems, etc.
  • A little more pricey than other NMN supplements.

Elysium Basis


Servings Per Container:


Money-Back Guarantee:



$50 (Official Website)

Elysium Basis is next on our list of best NMN supplements in 2023. David Sinclair, the popular biologist, allegedly uses Elysium Health’s Basis NMN supplement. Elysium Health offers a range of NAD+ levels booster NMN supplements. Among Elysium’s best NMN supplements, Elysium Basis is the right choice when it comes to optimizing cellular health.

Elysium Basis NMN supplement is vegan and contains no artificial colors or flavors. This best NMN supplement is NSF-certified for sports.

Taking NMN supplements by Elysium Health will bring you multiple health benefits including better cellular energy, reduction in fatigue, DNA repair, healthy muscle functions, and healthy aging.

As for the Elysium NMN dosage, take two NMN pills in the morning.

About The Brand

Elysium Basis Nicotinamide Mononucleotide supplement is made by Elysium Health Inc. It is developed by Leonard Guarente who is the co-founder and chief scientist at Elysium Health. The other founders of Elysium Health Inc. are Eric Marcotulli and Dan Aliminana. Together, they established Elysium Health in 2014.

Elysium Health Inc. aims to make the best anti-aging supplements accessible to people. Elysium Health developed the Aging Research Center to understand aging better and design the best NMN supplements to provide access to breakthrough aging solutions that are clinically tested.

All the NMN supplements by Elysium are manufactured in the USA in a facility that is approved by the FDA.

How It Works

Elysium Basis can boost your NAD+ levels by 40%. Basis has high-purity nicotinamide riboside and antioxidant pterostilbene that helps Elysium’s best NMN supplements in the synthesis of nicotinamide adenine dinucleotide and protects your cells from degenerating.

In addition to that, the NMN product works to activate sirtuins, which are a class of proteins that regulate the health of your cells. Sirtuins can only function with the help of NAD+. Hence, the Elysium basis helps in the synthesis of NAD+ to boost the functioning of sirtuins. Better health of your cells means improved ability to combat the aging effects.

Pros And Cons

Pros of Elysium Basis are:

  • This top NMN supplement is NSF-certified and does not affect your anti-doping test results.
  • The NMN product is a safe option for adults.

Cons of Elysium Basis are:

  • The nicotinamide mononucleotide supplement is not safe for pregnant or breastfeeding women.
  • The statements made by this best NMN supplement are not approved by the FDA.
  • The NMN product contains 30 NMN pills that are not enough for a 30-day supply.

Life Extension NAD+ Cell Regenerator


Servings Per Container:


Money-Back Guarantee:

365-day guarantee


$40.50 (Official Website)

Life Extension NAD+ Cell Regenerator is among the best NMN (Nicotinamide Mononucleotide) supplements. It is similar to Tru Niagen and contains 300 gm of Niagen, a refined form of nicotinamide riboside chloride. The formula promotes the growth of NAD+ or nicotinamide adenine dinucleotide. The pure NMN supplement is non-GMO, vegetarian, and free of gluten.

The health benefits of Life Extension NAD+ Cell Regenerator include supporting a youthful appearance, healthy cellular metabolism and production of energy, fighting fatigue and boosting vitality, and improved brain function.

The recommended NMN dose of Life Extension NAD+ supplement is one capsule daily.

About The Brand

This NAD+ supplement is manufactured by Life Extension, based in Florida. Life Extension “The Science of A Healthier Life” is an expert in the anti-aging supplement line. With more than 40 years of experience, Life Extension began its journey to help people live their best lives and reduce aging effects in the 1980s.

In 1981, they introduced DHEA, an anti-aging hormone. Since then, their team of researchers and nutritionists has been developing and modifying their formulas to give people the confidence to age better.

99% of Life Extension supplements are manufactured in the USA and follow the guidelines to create high-quality supplements in nutrition science.

How It Works

You already know that the level of NAD+ decreases as you age. This decrease in the level of NAD+ leads to spells of fatigue. Life Extension NAD+ supplement helps in the production of NAD+ to help produce ATP (Adenosine Triphosphate).

Production of ATP helps your cell produce more energy and get rid of fatigue or tiredness. As a result, you can achieve peak vitality.

Life Extension works at the cellular level. So, NAD+ also helps in promoting the health of cells and protecting you against cellular aging.

Pros And Cons

Pros of Life Extension NAD+ supplement are:

  • The supplement does not contain any chemical or synthetic ingredients.
  • The ingredients and science behind it are backed by research and evidence.

Cons of Life Extension NAD+ supplement are:

  • The supplement may not work for everyone and remain ineffective.

Liftmode NMN Powder


Amount Per Container:


Money-Back Guarantee:

90-day refund policy


$67 (Official Website)

Liftmode NMN supplement contains 98% of pure NMN powder. The nootropic compound is vegan and free from any additives. The powder is scientifically tailored to produce NAD+ to promote the cell’s energy levels and repair cells.

Regular Liftmode NMN supplementation offers you many health benefits such as enhanced energy and vitality, cellular renewal, and improved mitochondrial health. Additionally, the Liftmode NMN powder also promotes eye health.

The recommended NMN dose of Liftmode NMN supplement is 50mg per day. Each unit contains 100gm of nootropic compound. So, you can utilize the unit in two batches daily.

About The Brand

Liftmode manufactures this NMN powder. Liftmode is operated by Synaptent LLC, based in Chicago. It was established in 2010 and has been driven to provide cutting-edge solutions for physical and cognitive health.

On their team, they have Armand Tuzel, Tulin Tuzel, and Dr. Karen Vieira. With the help of its team, Liftmode manufactures top-quality dietary supplements that are tested and science-based.

The supplement is manufactured in their special in-house facility with proper care following all standard procedures.

How It Works

The supplement is designed to keep MNM stable and stop it from degradation. Research has shown that MNM can degrade into nicotinamide if it comes in contact with moisture or heat. By preventing NMN degradation, Liftmode MNN powder continues to supply MNM to your cells.

This precursor helps in the synthesis of NAD+ which protects your cells from the effects of aging. Taking this powder daily boosts the health of cells and promotes longevity.

The supplement also helps in improving mental focus and brain function as NAD+ ensures that your cells do not degenerate and function properly.

Pros And Cons

Pros of Liftmode Pure NMN powder are:

  • Liftmode powder offers an affordable price.
  • It is HPLC-tested and safe to consume.

Cons of Liftmode NMN powder are:

  • NMN powders may not dissolve properly. So, the supplement may not be easier to consume.

What Metrics Did We Consider For Ranking The Best NMN Supplements?

When ranking the best NMN (Nicotinamide Mononucleotide) supplements, we assessed several key metrics to ensure the quality, effectiveness, and safety of these products. Here are the metrics we considered:

NMN Purity

When ranking the best NMN supplements, we prioritize the purity of NMN within each product. Purity directly impacts the quality and effectiveness of the supplement. Higher purity levels mean you’re getting a more concentrated and potent dose of NMN, which is crucial for achieving the desired health benefits.

Supplements with lower purity may contain impurities or filler substances that dilute the active ingredient, making them less effective. Therefore, we give preference to products with the highest levels of pure NMN to ensure that users can reap the full benefits of this vital compound.

Dosage Accuracy

Another critical factor in our ranking process is the accuracy of the supplement’s dosage compared to what’s stated on the label.

Deviations from the claimed dosage can have a significant impact on the supplement’s effectiveness. If a product doesn’t deliver the specified amount of NMN, it may not provide the desired health benefits, and users might end up taking more or less than intended.

To ensure you’re getting what you pay for and that the supplement can deliver the expected results, we carefully assess the accuracy of the dosage in our rankings.


We also consider the bioavailability of NMN when evaluating the best NMN supplements. Bioavailability refers to how effectively your body can absorb and utilize NMN from the supplement.

Since NMN’s absorption can be challenging, supplements with enhanced bioavailability or specific delivery mechanisms are favored in our rankings.

These products are designed to optimize NMN’s absorption, ensuring that your cells receive the maximum benefit from this essential compound. Supplements with higher bioavailability tend to be more effective, allowing you to make the most of your NMN supplementation and support your NAD+ levels more efficiently.

Third-Party Testing

Imagine you’re hosting a dinner party, and your guests have high expectations for a gourmet meal. You’d want to ensure that the ingredients you use are of the utmost quality, right? Well, the same applies to NMN supplements.

We take third-party testing seriously because it’s like having a food critic taste-testing your dishes to confirm they’re as delicious as you claim. When we rank NMN supplements, we keep an eagle eye out for those who have undergone this rigorous examination.

Why? Because it’s the golden standard for ensuring that what’s on the label is what’s in the bottle. It’s like a guarantee that you’re not getting a reheated TV dinner but a five-star culinary experience.

NAD+ Boosting Efficacy

Now, let’s get down to the nitty-gritty – the NAD+ boosting efficacy. After all, this is the main event when it comes to NMN supplements. Picture NAD+ as the fuel that powers your cellular engine. You want a supplement that revs up that engine to maximum capacity, right?

Our rankings consider just how well a supplement can crank up those NAD+ levels. We’re not interested in a sluggish engine; we want a Formula 1 race car. So, when we evaluate NMN supplements, we look for the ones that deliver on their promise to give your cells the turbo boost they deserve.

Ingredient Synergy

We examine whether a supplement goes the extra mile by including ingredients like resveratrol or pterostilbene. These are like sidekicks that compliment NMN’s efforts, supporting NAD+ production and overall cellular health.

It’s like having Batman and Robin on your supplement label – a dynamic duo that ensures your cells stay in tip-top shape. When ranking NMN supplements, we appreciate those who understand the power of a good sidekick.

Form of NMN Dose

When ranking the best NMN supplements, one crucial metric we considered is the form of NMN used in the product. Specifically, we looked for supplements that contain NMN in its active and stable form, such as beta-NMN.

Why is this important? Well, the form of NMN matters because it directly impacts bioavailability and effectiveness. Beta-NMN is known for its superior stability and bioavailability compared to other forms. This means that your body can absorb and utilize it more efficiently, ultimately leading to better results when it comes to increasing NAD+ levels.

So, when evaluating NMN supplements, we gave higher rankings to those that utilized beta-NMN or similarly stable forms, as they offer a more potent and reliable way to boost your NAD+ levels effectively.

Manufacturing Process

Another critical factor we considered in ranking the best NMN supplements is the manufacturing process. It’s not just about what’s in the supplement; it’s also about how it’s made.

We thoroughly investigated the manufacturing processes of these supplements to ensure they adhere to strict quality control standards. Why is this essential? Well, a high-quality manufacturing process minimizes the risk of contamination or degradation of NMN during production.

Supplements that undergo rigorous quality control measures are more likely to deliver the potency and purity they claim on the label. This means you can trust that what you’re putting into your body is exactly what it says it is, without the worry of impurities or loss of effectiveness due to poor manufacturing practices.

In our rankings, supplements with a well-documented and stringent manufacturing process received higher scores, as they provide a higher level of confidence in the product’s quality and efficacy.

Unlocking the Potential: The Benefits of NMN Supplements

As we age, NAD+ levels naturally decline, which has sparked interest in NMN supplementation to counteract this decline. Here are some of the potential benefits of consuming NMN supplements:

Longevity and DNA Repair

One of the primary benefits associated with NMN supplementation is its potential to increase longevity. NMN acts as a precursor to NAD (Nicotinamide Adenine Dinucleotide), a molecule crucial for various cellular functions.

NAD activates a group of proteins called sirtuins, known for their role in repairing damaged DNA and regulating cellular processes. Sirtuins are linked to longevity as they help maintain genomic stability.

Research has shown that elevated NAD levels, facilitated by NMN supplementation, can promote sirtuin activity, potentially enhancing DNA repair mechanisms. This cellular maintenance may contribute to increased lifespan.

On the contrary, low NAD levels are associated with age-related diseases, suggesting the importance of maintaining adequate NAD levels for overall health and longevity.

Studies have demonstrated the role of NAD in DNA repair and its connection to longevity. The activation of sirtuins by NAD has been extensively researched, with promising implications for age-related diseases.

Neuroprotective Effects

NAD is believed to play a crucial role in protecting the brain from oxidative stress and mitochondrial dysfunction. Research suggests that NAD modulates the production of proteins that help safeguard brain cells against damage, making it potentially beneficial in combating neurological diseases such as Alzheimer’s.

Oxidative stress and impaired mitochondrial function are key factors in the development of neurodegenerative conditions. By promoting cellular health and reducing these stressors, NAD, when boosted by NMN supplementation, may contribute to better brain function and potentially reduce the risk of age-related cognitive decline.

While studies on NMN specifically are ongoing, research on NAD’s neuroprotective effects is well-documented. Studies have highlighted NAD’s role in mitigating oxidative stress and supporting brain health. NMN’s potential in this context is promising but requires further investigation.

Cardiovascular Health

NMN supplementation may have a positive impact on heart health by increasing NAD levels. Elevated NAD levels are associated with improved vascular function and the reversal of age-related arterial damage, which can be a significant contributor to heart disease.

Research in animal models has shown that high NAD levels in the blood can help maintain arterial health. By mitigating age-related changes in blood vessels, NMN supplementation may play a protective role against heart disease.

Animal studies have provided evidence of the cardiovascular benefits associated with increased NAD levels, which can be facilitated by NMN supplementation. However, human trials are needed to confirm these effects in humans.

Circadian Rhythm Regulation

NMN has shown promise in helping regulate the body’s internal clock, potentially easing issues like jet lag and circadian rhythm disorders. NAD, influenced by NMN levels, is involved in various processes related to circadian rhythms, including the synchronization of biological clocks.

Research indicates that NMN may assist in adjusting the body’s internal clock, thereby alleviating the disruptions caused by time zone changes or irregular sleep patterns.

Muscle Health and Aging

NMN supplementation has demonstrated promise in supporting aging muscles. Studies in older mice have shown that elevated blood NAD levels, facilitated by NMN, can lead to improved muscle function, strength, and endurance.

Age-related muscle decline is a common concern, but NMN’s potential to enhance NAD levels may help combat this issue by promoting healthier muscle tissue.

Animal studies have provided encouraging results regarding NMN’s impact on muscle health in aging. However, human trials are necessary to validate these findings and explore NMN’s effects on muscle function in humans.

It’s crucial to note that while the benefits discussed are based on the role of NAD, NMN supplementation is an emerging area of research that shows promise in enhancing NAD levels. Further clinical studies are needed to establish the specific benefits of NMN in humans comprehensively.


Which NMN Supplement Is Good For Heart Health And Insulin Sensitivity?

It is a scientifically proven fact that NMN can protect your heart and improve its function in stressful situations. Similarly, some supplements help in improving insulin sensitivity. So, you can choose any of the abovementioned NMN supplements. However, note that these NMN supplements are designed to combat aging effects. Their primary function is not to improve the health of your heart or reduce insulin resistance.

Do These NMN Supplements Really Contain Pure NMN?

Yes, all the supplements that we have mentioned contain a high quantity of pure NMN. To formulate the formula around 98% or 99% pure NMN is mixed with other natural compounds to make the formula more effective. However, the form of the NMN is pure with no artificial or dangerous components.

Final Verdict

While we can’t comment on what specific NMN brand David Sinclair recommends, we highly recommend the above-mentioned NMN brands. The anti-aging supplements are a safe choice for your DNA health and overall health. Other supplements may not offer you a natural way of NMN supplementation.

Along with NMN supplement products, give your lifestyle a makeover by changing your diet and adopting a routine that includes physical activities and exercises. You can also include vitamin B3 in your diet to give the NMN products a helping hand.

Finally, if you are wondering where to buy NMN supplements then, you should buy NMN supplements directly from the official websites of the brands to get your hands on high-purity NMN supplements.


The news and editorial staff of Sound Publishing, Inc. had no role in the preparation of this post. The views and opinions expressed in this sponsored post are those of the advertiser and do not reflect those of Sound Publishing, Inc.

Sound Publishing, Inc. does not accept liability for any loss or damages caused by the use of any products, nor do we endorse any products posted in our Marketplace.