Calibrate Reviews: Legit Doctor-Prescribed GLP-1 Weight Loss Medications for Metabolic Reset?

Are you looking for a program that will offer sustainable weight loss results? Calibrate is a comprehensive program targeting your metabolic health through food, sleep, exercise, and emotional health. It helps you make healthy lifestyle changes and provides accountability coaching and access to expert guidance.

The following Calibrate review will help you understand more about the program.

What is Calibrate?

Calibrate is a weight loss program designed to help treat obesity and overweight. It focuses on metabolic reset and the pillars of metabolic health, including food, sleep, exercise, and emotional health. The program runs for one year and provides effective results.

The program contains doctor-prescribed FDA-approved medication, one-on-one accountability coaching from experts, customizable plans for lifestyle changes, and more. It provides a holistic approach to weight reduction.

Calibrate provides sustainable weight loss by improving your metabolic health over 53 weeks. You will find biweekly video sessions with a health expert to improve your progress. The well-thought program covers all the bases of healthy weight loss. Calibrate doctors prescribe GLP-1 metabolic health medication that boosts digestion, controls appetite, and enhances metabolic function.

The experts help you incorporate behavioral changes to set you up for long-term weight loss. Calibrate members can talk to experts in the Medical channel app or reach out through the support channel.

The Calibrate doctors use lab results, members’ health history, and daily tracking measurements to treat people. According to the website, Calibrate helps you lose 10% of your initial body weight. The program is designed for patients between 18-64 who have a BMI of over 30 or over 27 with pre-existing metabolic conditions.

The team at Calibrate will help you get insurance coverage for your GLP-1 medication if necessary. If you fail to secure coverage, you are eligible for a refund.

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How Does Calibrate Work?

Calibrate aims to help members attain an average of 15% weight loss and sustain it at 18-24 months. The program requires individuals who are genuinely dedicated to lose weight and adjust their lifestyle. Members can participate in the program in the comfort of their homes, as there is no need for in-person appointments. However, calibrated doctors can offer in-person appointments at selected locations across the US.

The program helps you reach metabolic reset, which involves the four pillars of metabolic health. It enables you to make healthy food choices, create a consistent sleep schedule, exercise, and incorporate stress-reducing techniques. You will implement your goals through your coach’s guidance during the one-on-one coaching sessions.

These are the four stages of learning in Calibrate:

Learning: 1-3 months- involves setting goals, meeting with the Calibrate doctor, and reading 1-2 lessons on the Calibrate app weekly. Level 1 establishes a foundation and helps understand the basics of metabolic health.

Practicing: 3-6 months- throughout the program, you will have personal weekly coaching with your expert to discuss your progress and goals. You are required to read two lessons per week on the Calibrate app. The program welcomes you to select classes that focus on areas you are interested in.

Setting: In 6-9 months, you will continue with your biweekly videos, lessons on the app, and focus classes; you can modify your habits and set your schedule on the pillars you want to focus on.

Sustaining: 9-12 months- the program sets you up for long-lasting and sustainable results. It helps you stick to the healthy habits you’ve created.

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What to Expect from Calibrate

Here are some of the things to expect during the one-year Calibrate journey:

Biweekly Video Checks

The program assigns an accountability coaching team to conduct video coaching to help you learn how to make lifestyle changes. The team will help you stay on track and monitor your progress.

The video coaching sessions are 26 annually and usually take approximately 15 minutes. The accountability team provides recipes, classes, a personalized curriculum, and expert counseling to assist you in meeting your goals.

Doctor-prescribed GLP-1 medication

Calibrate doctors prescribe GLP-1 medication that targets the underlying cause of weight gain. The medication mimics the effects of GLP-1 hormone produced in the gastrointestinal tract, which helps maintain healthy blood sugar levels and control insulin release. The doctors prescribe medications like Ozempic, Wegovy, Saxenda, and Mounjaro.

The Benefits of GLP-1 Medication

Reduce inflammation- GLP-1 medications activate the GL-1 receptors, which inhibit inflammatory pathways, thus regulating inflammatory response. The receptors also produce reactive oxygen species (ROS), which prevents oxidative damage and inflammation. The medication improves endothelial function, which helps reduce vascular inflammation.

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Regulate digestion- the medication ensures healthy digestion by slowing food movement from the stomach to the intestines.

Enhance metabolic function- GLP-1s stimulate insulin release in the pancreas, thus regulating blood sugar levels. It also causes an increase in energy levels by assisting your body to burn calories.

Reduce weight- GLP-1s mimic the action of GLP-1 hormone, which plays a vital role in appetite regulation. The medication activates GLP-1 receptors, promoting a feeling of fullness that aids in weight loss. GLP-1 medication also delays gastric emptying, helping you stay longer without feeling hungry.

Support cardiovascular health- GLP-1 medications have demonstrated cardiovascular benefits by reducing the risk of major cardiovascular events, such as heart attacks and strokes, in individuals with type 2 diabetes. Activating GLP-1 receptors regulates blood pressure, thus supporting cardiovascular health.

GLP-1 medication

Wegovy (semaglutide)

Wegovy is an injectable GLP-1 medication that the FDA approves. It is used for chronic weight management and helps treat obesity. The medication works with the Calibrate metabolic reset program to help you attain sustainable weight loss results.

Wegovy supports people with diabetes or impaired glucose tolerance. It activates the GLP-1 hormone to send signals to the brain, muscles, liver, pancreas, and stomach whenever you eat. You can inject Wegovy once weekly on the same day of the week in the abdomen, thigh, or upper arm.

The maintenance dosage is 2.5mg once per week. However, you can start with a dosage of 0.25mg and gradually increase after four weeks.

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Ozempic (semaglutide)

Ozempic is a weekly injectable GLP-1 medication prescribed by Calibrate doctors. It helps treat type 2 diabetes, support healthy blood sugar levels, and manage weight. The medication works by signaling the brain to stop eating.

It activates the GLP-1 hormone to send signals to the muscles, stomach, liver, pancreas, and brain. Ozempic increases the feeling of fullness and combines with the four pillars of metabolic health for effective weight loss.

The FDA dosage recommendation is once weekly on the same day of the week. Ozempic may have side effects like nausea, diarrhea, vomiting, constipation, stomach pain, headache, tiredness, upset stomach, heartburn, bloating, and dizziness.

Mounjaro (tirzepatide)

Mounjaro is a dual GIP and GLP-1 agonist that helps treat type 2 diabetes. The injectable medication helps balance blood sugar levels and promotes weight loss. It works best alongside lifestyle changes, coaching, and support from Calibrate experts. The active ingredients in Mounjaro prevent insulin resistance and treat obesity.

You are eligible to take Mounjaro if you are using type-2 diabetes medication like metformin. The maximum Mounjaro dosage is 15mg. However, depending on your tolerance, you should start with 2.5mg and increase after four weeks. The injectable drug might have side effects such as indigestion, nausea, vomiting, decreased appetite, constipation, and abdominal pain.

Saxenda (liraglutide)

Saxenda is an FDA-approved GLP-1 medication that helps manage weight loss and regulates blood sugar levels. Like other GLP-1 drugs, Saxenda also mimics the incretin hormone, delaying gastric emptying and promoting a feeling of fullness.

The medication helps you lose weight and stick to healthy habits. You can inject Saxenda once daily. The starting dosage is 0.6mg per day for one week. Increase the dosage gradually until you reach 3mg, the full maintenance dosage.

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Rybelsus (semaglutide)

Rybelsus is an oral GLP-1 medication that controls blood sugar and reduces weight. The medication works best alongside the pillars of metabolic health. It works by mimicking the incretin hormone, increasing insulin production, and lowering glucagon production for healthy blood sugar levels.

You are eligible for Rybelsus if you are already under diabetes medication. The Calibrate team will work with you through the recommended dosage and advise you when to take it. The starting dosage is usually 3.0mg for 30 days. After the first month, you can increase your dosage to 7.0mg. Depending on your tolerance, your doctor may increase your Rybelsus dosage to 14.0mg daily.

Trulicity (dulaglutide)

Eli-Lilly and Company manufactures Trulicity, which mimics Incretin hormones that signal the brain when you consume food. The brain reacts by producing various neurotransmitters that support the feeling of fullness and delay stomach emptying. According to the manufacturer, Trulicity supports insulin response to high blood sugar levels after meals.

Trulicity works with the four pillars of metabolic health to maximize your weight loss results. Most Trulicity users start seeing positive results like less appetite within the first week. The injectable medication is easy to take. You can use Trulicity once weekly, any time of the day, with or without food. The pens are available in 0.75mg, 1.5mg, 3.0mg, and 4.5 mg.

Common Trulicity side effects include nausea, constipation, stomach discomfort, vomiting, less appetite, indigestion, and fatigue.


  • Calibrate provides sustainable weight loss;
  • Doctors and experts formulate the program;
  • Calibrate works alongside lifestyle changes and medication;
  • The team at Calibrate helps users navigate through insurance coverage;
  • Calibrate is suitable for both men and women;
  • The program provides accountability through biweekly video coaching;
  • FDA approves the GLP-1 medication prescribed by Calibrate doctors;
  • Calibrate is flexible and has no restrictions.


  • Calibrate may be expensive for some people;
  • The one-year program is only accessible on the website.

Customer Reviews

The official Calibrate website has real stories about customers who have benefited from the program.

Donya says, “I’ve lost 23% of my body weight or about 49 pounds. I have so much more energy, and I’ve also noticed an improvement in my mood. Plus, my A1C and cholesterol levels are down, which has made me and my doctor very happy.”

Jason writes, “In addition to increasing my muscle mass, I’ve noticed that I have a lot more energy during the day. I feel more confident with myself and with how I see myself, and truly believe that my emotional health—in addition to my physical health—has improved.”

How to Use the Calibrate Program

Here are the steps to reset your metabolism:

Step 1: Check your eligibility- it involves a 2-minute quiz to check eligibility. The requirements include:

  • Be of ages 18-64 years;
  • Have a BMI of over 30 or over 27 or with a metabolic condition;
  • Have an employer insurance;
  • Reside in the United States;
  • Not be pregnant or breastfeeding;

Not have medical conditions like type 1 diabetes, cancer, active gallbladder disease, history of thyroid cancer, pancreatitis, an active eating disorder, active substance abuse, or have done bariatric surgery over the past 18 months.

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Step 2: Complete a health intake form- it entails answering questions about your medical history, which usually takes about 20 minutes;

Step 3: Get your labs- Calibrate and send you to your healthcare provider or a local healthcare provider to get Cr/GFR for your kidney function, hemoglobin A1C, or fasting glucose to measure your thyroid-stimulating hormone and blood sugar;

Step 4: Review the welcome kit- Calibrate will send a welcome kit in your email, including a smart scale that you can sync to the Calibrate app and orientation tools;

Step 5: Download the Calibrate app- feel free to download the Calibrate app to monitor your progress, reach out to the Calibrate team of experts, and complete your lessons;

Step 6: Meet your Calibrate doctor- your doctor will invite you to a virtual meeting to review your health history and lab results;

Step 7: Begin the metabolic reset program– you can now begin the program running for one year.

Pricing and Refund

According to the official website, the price of the Calibrate program is $1,749, a one-time payment. The team at Calibrate will help you access GLP-1 medication for $25/month. The team will also help you navigate through insurance coverage. If there are no low-cost GLP-1 medications, you will receive a refund of $250 less for the initial doctor’s appointment. Customers can reach out to customer service by logging into the App or sending an email to the medical and support teams at:


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Calibrate is a one-year program focusing on maintaining healthy blood sugar levels and reducing weight. It provides long-term and sustainable weight loss results without invasive procedures.

The program provides lessons and tools to make healthy lifestyle changes. You will access video coaching sessions and doctor-prescribed GLP-1 medication, depending on your condition. Calibrate helps reduce inflammation, control appetite, support heart health, treat type 2 diabetes, and prevent insulin resistance.

Before joining the Calibrate program, you have to check for eligibility. The program is formulated by doctors and experts who rely on scientific studies; therefore, it is safe. Many Calibrate users have benefited from the program and are enjoying sustainable results.

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