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Best Immunity Supplements – Top Immune System Boosters 2021

The immune system in the human body holds the natural defense against infections and illnesses. Having a great immune system is crucial for the overall good health of a person. Several people have perfect biological immune systems, and they lead healthy lives without getting any allergy attacks. The rest must have a healthy lifestyle and strict diet habits to help improve their body’s natural immunity.

Many people consider taking supplements trying to suppress their allergies. What they don’t know is that allergies are a defense mechanism by the body to fight off foreign bodies. When your immune system comes into contact with elements like pollen or some food-like pathogens, it launches an attack to defend itself from the foreign substances.

When your entire body is wholesome, the immune system helps fight harmful foreign bodies that cause illnesses. Minor responses to the immune system include responsive cough and sneeze reflexes or even tears when something foreign enters your nose or eyes. Properties such as antibodies are beneficial in the immune system.

The antibodies are simple proteins used to fight infections and diseases in your body. We readily find the best superfoods to boost your immunity in our kitchens and local grocery stores. These foods include leafy greens, berries, oranges, elderberries, dark chocolate, red grapes, turmeric, and ginger.

Today, many people have to take supplements to help boost their natural immunity. They use many scientifically proven compounds as supplements, namely zinc, Vitamin C supplements, herbal, and various plant extracts.

Top Immune System Boosters in 2021

Currently, we have hundreds of supplements that manufacturers and sellers claim to be the best immune booster in the market, which is false. Several supplements don’t work as the manufacturers claim they would. However, we have done thorough research, and listed below are the best immune system boosters you should consider the next time you are making a refill.

Organixx 7M


Organixx 7M has mushroom extracts and several other ingredients which are vital for immune function. The critical element in the supplements include extracts from the maitake mushroom, reishi mushroom, and shiitake mushroom. The above mushroom supplements are the most popular and clinically proven beneficial extracts highly beneficial for human immunity. The mushroom extracts are full of beta-glucans that are packed with antioxidants and anti-inflammatory properties.

The manufacturers have also added several other ingredients on top of the mushroom extracts, including turkey tail mushroom extracts; 7M uses cordyceps, lion’s mane, known for their powerful ability to help the immune system. They recommend the consumer to use it daily to support the immune system by reducing inflammation in the body, boosting digestion, and supporting the immune system by protecting the body against aches and pain in the body.

VitaPost Immune Support


VitaPost Immune Support provides the consumer with several botanical extracts that nourish your entire immune system. According to the manufacturer, the supplements contain vitamins, some herbal extracts, and several other vital ingredients in the immune system.

While making the formulation, they use a blend of both traditional and modern elements, which include arabinogalactan, green tea, quercetin, vitamin C, vitamin E, and beta-glucans, to mention a few. Some ingredients mentioned above work by adding antioxidants to the human body that help to support your immunity.

The other ingredients target other aspects of your immune system to bring out an entire body’s health. The supplements come as a capsule that is easy to swallow. They make each tablet with over a dozen proven ingredients, and it’s one of the best supplements in the market for the immune system. It’s also very affordable, going for only $13.95.

VitaPost Immune Complex


VitaPost Immune Complex supplement has several immune support components that are vital to the human body. Some ingredients used to formulate the supplement include Echinacea, probiotics, and elderberry. The elements used to make the supplement unique make it a unique approach to supporting human immunity.

The ingredients mentioned above are the strongest in the natural world for immune support. Experts say that the elderberries massively reduce the days taken for the cold and flu symptoms to disappear. We believe the Echinacea also functions in the same way.

Probiotics are beneficial to the body, especially the digestive tract, the primary organ responsible for the human immune system. In the human body, 70% of the immune system is in the digestive system tract. Consuming the VitaPost Immune Complex ensures support for your gut inside out for a small price of $11.95.

Zenith Labs Nano C


Dr. Ryan Shelton of Zenith labs created the Zenith. Nano C is a vitamin C supplement that one should take several drops per day to ensure your body has a significant amount of vitamin C required in the body.

According to experts, Vitamin C is nature’s best antioxidant which is highly beneficial in the human body. When you consume the Nano C, you get the Nano version of the vitamin C, which is over 1000 times smaller than the kind found in nature. The manufacturer makes them extra small to ensure your body absorbs them more easily. They then quickly enter your bloodstream to help fuel your immune system cells.

A report from Dr. Shelton and the Zenith Labs states that the Nano C will help fortify your body’s immune system and enhance absorption with nanotechnology, which helps promote the production of antibodies. The antibodies are functional, especially where the immune system fights bacteria or viruses and quickly recovers. One dose of the supplement sells at $49 only.

Mushroom Defense


They are great at supporting the immune system. Experts claim that mushroom extracts can fight fatigue and protect a person against a decline in cognitive capabilities. More studies reveal that mushroom extracts are great for improving and sharpening human memory and focus.

The manufacturers use unique ingredients that are not available in other mushroom supplements. The rarest element is the Agaricus blazei, a mushroom extract found in the mountain village in Sao Paulo, Brazil. Different clinically tested mushroom kinds include shiitake lion’s mane, reishi, cordyceps Sinensis, Chaga, maitake, and turkey tail.

Mushroom Defense manufacturers say that their supplement helps protect consumers against viral and bacterial threats and supports energy and cognitive abilities. The seller has a return policy of up to 67days—any consumer who believes in the power of mushroom extracts. Mushroom defense is the best supplement for you that goes for less than $60.

Epishield Plus


The manufacturer claims that the Epishield Plus dietary supplement helps boost your immunity in two hours or fewer after consumption. The supplements use common ingredients readily available in other supplements, including mushroom extract vitamin C and vitamin D. What makes it more unique is the special ingredient that is not very common in another supplement, the fermented yeast. The fermented yeast in the Epishield Plus helps to maintain a robust immune system for the consumer.

Each bottle sells at only $49, but this does not stop consumers from ordering the supplement out of stock. It’s the second supplement on the list whose formulations include EpiCor, a dried fermented yeast extracted from Saccharomyces cerevisiae. You may get yeast extract, Vitamin C, and D from several other supplements. Epishield Plus is unique and more preferred from the rest of its kind is the fermented yeast extract added to the supplement.

Advanced Bionutritionals Resistol


The Advanced Bionutritionals Resistol is a healthy supplement that helps support the immune system of the consumer. It’s formulated using five potent herbs: Platycodon, Andrographis, prickly chaff flower, licorice, and eleuthero. Many people preferred taking them daily to strengthen their immune systems.

Many supplements in the market are currently beneficial to the body, as they are full of great vitamins for boosting immune systems. However, for the Bionutritionals Resistol, the manufacturer has taken a different approach and used a blend of various herbs absent in other formulations. The supplement is rich in Andrographis, eleuthero, and Platycodon, the best support for the immune systems. Additionally, a bottle goes for only $29.95, which is very fair compared to the rest of its kind.

Immunity Formulas Immune Support


They formulate the supplement using some high-grade therapeutic herbal essential oils. The manufacturer claim that Immunity Formulas Immune Support is the best for dealing with any type of immune and virus problems in the body. According to the manufacturer, the supplement helps the consumer build up a natural defense against any viral infection and also helps purify the air. The manufacturer advises the consumers to take the supplement daily to realize the power of the essential oils.

Essential oils used to formulate the supplement are cinnamon, essential oils, oregano, peppermint, turmeric, and lemon. Experts claim that the essential oils available in Immune support can support the immunity of the consumer in a small way. However, some studies seem not to support the above claim. However, one significant thing about the formulation is that it can diffuse it in the air around the consumer if they decide to apply it directly to their skin.

The mode of application of the supplement makes it more appealing to most people. They feel it must be a great supplement if one can breathe it or absorb it through the skin. The supplement is relatively affordable for its type going only for only $64.99.

VitaPost Turmeric & Ginger


The third vita post supplement and one of the Best Immunity Boosters on this list are the VitaPost Turmeric & Ginger. The accessories blend in Bioperine in its formulation to ensure the consumer has a solid immune system and joints by flooding the consumer’s body with antioxidants beneficial for the body.

Many people consume turmeric and ginger supplements to keep their bodies’ immunity and overall health and wellness in perfect conditions. Turmeric and ginger are two superfoods known to have properties beneficial for a person’s immunity, which is why VitaPost Turmeric & Ginger is the best supplement to use.

The supplements formulation comes in capsules containing 500mg organic turmeric and 100mg ginger. They have also added 50mg of turmeric, including 95% curcuminoids and 5mg black pepper extracts crucial to the supplement’s absorption into the body. If you are looking for a potent turmeric and ginger supplement, this is the one you will get at an affordable price of $23.95.

Immuno Defense 4x


The Immuno Defense 4x formulation comprises a critical ingredient that is great for boosting immunity. The elements include bromelain, EpiCor, vitamin D3, and quercetin. Immuno Defense 4x formulates the supplement by combining a few ingredients to make a potent formulation. Unlike a few others who use many elements, their supplements don’t benefit the human body.

The supplement formulation comprises 50mg of bromelain, 500mg of EpiCor, 166% DV of vitamin D3, and 500mg of quercetin. The supplement is the cheapest, going for only$44.95 for a single bottle with 60 capsules.

Doctor G’s Naturals Q-Ion Immune Defense


The supplement is a creation of a board-certified physician known as Dr. John Gordon. He used his medical knowledge to formulate the supplement and added powerful supplements like bromelain, green tea extract, quercetin, and zinc. The formula has incorporated powerful Ion-Blast Technology that adds an extra level of bioavailability in the quercetin and zinc, which allows the human body to absorb the supplement faster and with more ease.

The manufacturer claims that Doctor G’s Naturals Q-Ion Immune Defense supplement is doctor approved. It means at least one or more doctors have approved the use of the supplements and believe the supplements are great for boosting the immune system.

The manufacturers claim that the formulation has powerful anti-inflammatory properties that allow the consumer’s body to fight any viral infections and strengthen the immune system. The manufacturers say that the properties in the supplements are strong enough to protect the consumers against any dangerous pathogens in the body. The supplement retails at only $79.95.

Immunity 911


According to the manufacturer, the Immunity 911 supplements contain the most substantial immunity properties and ingredients that enable the body to fight against infections. The immunity 911 uses a wide range of components in a single dose capsule.

However, the doses are not as high as the other competing brands on this list, considering the PhytAge Labs claim. They say that they guarantee the supplement will work fast on your body. But their doses contain tiny doses of ingredients. For example, it only has 33% DV of vitamin C and 133% of vitamin E, lower than any supplement formulation on our list.

They have included a strong dose of green tea leaf extract, red raspberry fruit extract, and Graviola leaf extracts, which are the primary ingredients in the formulation. It makes it hard to evaluate the Immunity 911 health claims as they lack transparency. PhytAge Labs guarantees the consumers that the component in the formulation of Immunity 911 will work using herbs, super-fruits, and mushroom extracts. Their prices are also high, one bottle going for $69.95.

BioShield MD


Compared to others on the list, the BioShield MD supplement has many benefits in the human body, including supporting the entire immune system, mental health benefits, providing natural energy, and improving joint health. Dr. Mark Rosenberg, from SunCoast Science, created the formulation. He has designed the supplement to provide maximum bioavailability and clinically effective dosages vital in the human body.

The BioShield MD supplement is the best on the human body as it is formulated with the best and clinically tested ingredients that are the best for the consumer’s immunity. They are added in the formulation of the correct dosage in the supplements. Many supplements out there are full of low dosages and inferior ingredients. Luckily, BioShield MD emphasizes using potent ingredients like tart cherry extract, quercetin, green tea extract, cocoa extract, resveratrol, and curcumin.

All the ingredients mentioned above have powerful properties rich in flavonoids and antioxidants that help several ways support consumers’ health and immune health. They sell the supplement at a very affordable price of $49.95.

Ranking Methods Used For The Best Immunity Boosters

Every supplement manufacturer out there claims their products support the immune function fully. Some have questionable herbal extracts that are heavily backed up by scientific research. A comparative evaluation was conducted, and we could determine the best and the worst immune supplements. The following are the qualifications we used to rank the above supplements.

Cost and the Value

The cost and value of the immune boosters differ from one company to the other. Even when purchasing, one buyer will prefer products selling at lower prices, and another will go for the most expensive one. While creating this list, we ensured to include a range of products even though we considered the quality value of the product over its price.

Honesty when listing the health benefits

According to the FDA, regulation manufacturers cannot claim that their supplements can cure or improve consumers’ health. Supplements are only used to support a human’s health. Currently, in the market, we have very many supplements that have dropped the term booster.

They have advertised their products as virtual cures for several common ailments. Some even claim that their supplements can prevent viral infections like COVID-19. These claims are false, and we have avoided such claims when creating the above list.

Where the supplement was manufactured

We put many considerations into supplements that were manufactured in recognized facilities that have been certified. During our research, we discovered several companies source their products from cheap manufacturers overseas.

The products they get have lower standards and inferior quality. However, a few good ones use local facilities that are FDA certified and approved by the national regulatory board. These are the high-quality supplements and most of which we have highlighted above.

Scientifically proven ingredients

Many supplements we discussed used several common properties in their formulation: vitamin C, vitamin D, elderberry extracts, probiotics, and zinc. Scientific evidence had scientifically researched all the supplements and backed up. Several experts have supported the study’s findings, and they agree the ingredients listed above have the ability and properties required to keep the immunity. The above-listed supplements had solid clinical proof to back up their functionality claims.

The manufacturer’s reputation

Many companies get into the supplements formulating business not to help people but to make quick money. They end up making immune boosters that don’t perform as they should, most of which are more harmful to the consumer. While compiling this list, we prioritize manufacturers that have been around for a while and have built up a powerful reputation by offering transparency and effective immune boosters.

The medical advisory board

The Best Immunity Boosters manufacturing companies have a medical advisory board that has several medical doctors. The medical doctor on the board helps with reviewing and coming up with formulations for the supplements. They use their expertise in medicine and research extensively to ensure they develop a blend that will effectively boost the consumers’ immune system. Some manufacturing companies do not have an advisory board, and they create a lower quality that is less effective.

Dosage levels

Several manufacturers use the right ingredients when formulating the supplements but mess up the formulation when adding the wrong dosage levels. Other manufacturers use excess ingredients in their formulations but create supplements that are not even powerful enough to boost their immune systems. Supplements with robust and clinically proven dosages were favored while compiling the list of the ingredients.

Sources of their ingredients

A substantial number of immune boosters are formulated with several unique and healthy ingredients that are not common in others. An example would be the mushroom extracts from rare types of mushrooms. On our list, we gave priority to manufacturing companies that were honest with the supplements they used and where they sourced them.

The Side Effects of Immune Boosters

Immune boosters have no side effects, especially if they are taken as per the guideline provided. However, this is just an assumption for a healthy adult who is not taking any medications and consumes them.

The law states that the manufacturers must use ingredients and dosages recognized as Safe (GRAS) as per the FDA guidelines. The ingredients are safe for human consumption when administered to the consumers at the recommended dosage. Many reputable companies stick to the guidelines mentioned above, and thus it is tough to cause any side effects.

However, there is a possibility that a consumer may experience some minor side effects, as discussed below;

Common side effects

  • Nausea
  • Constipation
  • Intense abdominal pains
  • Headache
  • Cough

Uncommon side effects

  • Vomiting
  • Abdominal bloating
  • Backaches,
  • Chest pains
  • Pain in the arms and legs

Very Rare side effects

  • Neuropsychiatric Disorder

Talk to a doctor about your medical history before taking the immune boosters, especially for people under medication or who have chronic illnesses.

Scientific proof for Immunity Boosters

Scientists have carried out various studies and revealed that different herbs, fruits, vitamins, plant extracts, and minerals are beneficial for supporting the human’s immune function. Taking the said ingredients frequently helps strengthen your immune system, acts as a natural defense against any illnesses, and even slows down aging. Your immune system plays a critical factor in your overall health and wellness. Therefore, it’s advisable to take the Best Immunity Boosters daily.

However, one could consider alternative ways of boosting their immune system, for example, following a good diet and changing your lifestyle habits for the better. Examples of improved lifestyle habits include a balanced diet, adequate sleep, drinking enough water, and exercising. It will be hard for your body to defend itself if you consume unhealthy food and undertake unhealthy habits.

Several things can weaken your immunity, for instance, a poor diet. Adding too much sugar to your diet significantly weakens your immunity. Other poor lifestyle habits include excessive alcohol consumption, dehydration, poor sleeping habits, stress, and lack of extreme ad obesity.

Vitamin C

It’s a prevalent immune booster supplement widely added in various supplement formulations. Experts have revealed that Vitamin C helps your body, specifically the immune system, in several ways. The National Institute of Health advises that your body needs vitamin C to synthesize neurotransmitters, collagen, and L-carnitine.

Vitamin C is vital in your body for creating connective tissues that help heal wounds and act as an antioxidant. It targets disease-causing components throughout your body. Some researchers have revealed that the vitamin works to prevent and delay certain cancer types.

Vitamin D

People with vitamin D deficiency have shallow immune functions. It’s crucial to take a recommended amount of vitamin D daily to improve your immune function. They are linked to lack of vitamin D to increased risk of infections like colds and flu.

Before the invention of antibiotics, Vitamin D was widely used to treat viral diseases like tuberculosis. Vitamin D is readily available in several foods we eat. We also build our bodies to absorb vitamin D3 from direct sunlight and convert it to the highly required vitamin D.


On the above list, almost half of the immune boosters do not have protein in their formulation. Protein is the most crucial vital component in supporting a human’s immune system. Proteins contain amino acids, which are essential in the body. You can get amino acids from various foods we have on our daily diets, including eggs, soy, beans, yogurts, fish, poultry, beef, pork, and all kinds of nuts.

Proteins play a crucial role, especially in the intestinal cells. Up to 70% of the human’s immune system is found within your gut. It’s highly recommended to consume foods and supplements that are high in protein for a healthier gut.


Zinc supplements are best taken daily as they help strengthen your immunity. Zinc deficiency in the body results in poor immune system functions. People with lower zinc levels in their bodies are at risk of getting affected by factious diseases. Zinc is rich in anti-inflammatories and antioxidants, and therefore, even the slightest deficiency in zinc is critically harmful to one’s health, causing immune dysfunction. You can get zinc from various immune zinc supplements or eat foods like nuts, oysters, meat, and whole grains rich in zinc.


They are some of the best nutrients that one can eat to have a healthy gut. Probiotics are also the trendiest nutritional supplements everyone is currently taking. They are also accommodating with the prevention of viral infections. Some experts also claim that probiotics can treat and prevent seasonal allergies.


They are not very common, but the few people aware of their benefits use them extensively for their medicinal and health benefits. Many people have used the elderberry to treat and cure flu and cold symptoms for ages. Currently, some researchers are recommending elderberries to their patients. The elderberry extract is rich in vitamins, which make it a potent immune booster.


We have used Echinacea for medicinal purposes for the longest time. Recently experts officially validated it for use, and they claim it’s among the best immune boosters. A recent study reveals that using Echinacea even for a short time helps to reduce the severity of respiratory infections, especially when taken at the onset of the condition.


Ginger is a superfood that people have been using for years as a traditional medicine to treat several conditions. It is rich in antioxidants, anti-inflammatory and anti-bacterial properties that are beneficial for immune support.


It’s famously known and used for its antioxidant properties. If consumed daily, it helps boost your immunity, as it is rich in anti-inflammatory properties. The anti-inflammatory properties are mainly from the curcumin and curcuminoids found within turmeric. A recent study shows that turmeric is often poorly absorbed in the body, and it’s advisable to mix it with some black pepper extract for better absorption.

The ingredients mentioned above are very beneficial to the immune system. Several scientific studies prove the many theories we have seen. Consuming them in their natural form or supplements benefits your immune system and the gut, and, as a result, your total body health improves.

Similarly, it’s advisable to avoid bad habits like excessive alcohol consumption, smoking, poor sleeping habits, poor dieting, and lack of exercise. Consider taking the right immunity booster for you to help your body fight against infections by just supporting your natural immunity.

Learn more about the top-ranked immunity boosters.

RELATED: Noobru Shield Reviews – Is Noobru Immunity Boost Supplement Legit?

Affiliate Disclosure:

The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team and please know we only recommend high quality products.


Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.

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